import numpy as np
import matplotlib.pyplot as plt
from PIL import Image
from skimage import io,data
%matplotlib inline

img_name="C:/Users/Administrator/Desktop/test.png"
img=io.imread(img_name,as_grey=False)

rows,cols=img.shape[0],img.shape[1]

new1=img[0:rows//2,0:cols//2]
new2=img[0:rows//2,cols//2:cols]
new3=img[rows//2:rows,0:cols//2]
new4=img[rows//2:rows,cols//2:cols]

out=[new1,new2,new3,new4]
for i in range(4):
    plt.subplot(2,2,i+1)
    io.imshow(out[i]),plt.axis('off')